Job Title: Research Associate (Microbiology)
Telephone No: + 44 (0) 29 2041 6459
Email Address: email@example.com
Room Number: D2.02
I am currently undertaking my PgCTHE within the Cardiff School of Health Sciences at Cardiff Metropolitan University, specifically in the Department of Biomedical Sciences. I currently help deliver microbiology lectures at levels 4 and 5, practical classes at level 5, and supervisor level 6 final year undergraduate projects.
Modules I am involved with:
APS5015 Principles & Practice of Infection Science
POD4001 Podiatric Medicine
I am currently funded by the Hodge Foundation (previously Jane Hodge Foundation) looking into the treatment of opportunistic pathogens associated with pulmonary disease, more specifically those that persist to form chronic infections of the cystic fibrosis (CF) lung. Using manuka honey alone, and in combination with a range of therapeutic agents, we have shown excellent inhibitory efficacy against a range of CF pathogens, such as;
Burkholderia, Pseudomonas, Stenotrophomonas, Achromobacter, and
Staphylococcus to name but a few of the genera studied. Previous research has focussed on the conflict and cooperation of bacterial cells in mixed communities, the diversity of cells from a seemingly clonal population, and the spatial structure of small bacterial aggregates, and larger biofilms. Further to this, I have extensively the mechanistic effects of manuka honey on
P. aeruginosa growth, virulence, and biofilm formation.
Roberts, A. E. L., Maddocks, S. E. & Cooper, R. A. (2012) Manuka honey is bactericidal against Pseudomonas aeruginosa and results in differential expression of oprF and algD. Journal of Microbiology 158 (12), 3005-3013
Roberts, A. E. L., Maddocks, S. E. & Cooper, R. A. (2014) Manuka honey reduces the motility of Pseudomonas aeruginosa by suppression of flagella-associated genes. Journal of Antimicrobial Chemotherapy doi: 10.1093/jac/dku448
- Harrison, F.,
Roberts, A. E. L., Gabrilska, R., Rumbaugh, K., Lee, C., & Diggle S. P. (2015) A 1,000-year-old antimicrobial remedy with anti staphylococcal activity. mBio 6 (4), e01129-15
Roberts. A. E. L., Kragh, K. N., Bjarnsholt, T., & Diggle, S. P. (2015) The limitations of in vitro experimentation in understanding biofilms and chronic infection. Journal of molecular biology 427 (23) 3625-3792.
Roberts, A. E. L., Brown, H., & Jenkins, R. E. (2015) On the antibacterial effects of manuka honey: mechanistic insights. Research and Reports in Biology. 6 215-224.
- Melaugh, G., Hutchison, J., Kragh, K., Irie, Y.,
Roberts, A. E. L., Bjarnsholt, T., Diggle, S., Gordon, V., & Allen, R. (2016) Shaping the growth behaviour of biofilms initiated from bacterial aggregates. PLoS ONE. 11 (3) e0149683
- Kragh, K., Hutchison, J., Melaugh, G., Rodesney, C.,
Roberts, A. E. L., Irie, Y., Jensen, P. Ø., Diggle, S. P., Allen, R. A., Gordon, V. D., & Bjarnsholt, T. (2016) Roll of multicellular aggregates in biofilm formation. mBio 7 (2) e00237-16.
- Brown, H.,
Roberts, A. E. L., Cooper, R. A., & Jenkins, R.E. (2016) A review of selected bee products as potential anti-bacterial, anti-fungal, and anti-viral agents. Medical Research Archives 4 (8) 887.