Dr Sarah Maddocks

I teach microbiology on the Biomedical Sciences and Health Care Science BSc degree courses as well as on the MSc Biomedical Science degree course.  I am the pathway lead for the Biomedical Sciences strand of the MRes degree course.

I teach on the following modules:

• Principles and Practice of Infection Science (module leader) 
  
• Infection Science Specialism A and B (module leader)
  
• Biological and Laboratory Investigations of Disease
  
• Contemporary Topics in Biomedical Science
  
• Analytical and Diagnostic Techniques (MRes) 
  
• Research Methods in Biomedical Science (MRes)
  

I have supervised and continue to supervise a number of PhD students undertaking research within the field of biofilms, novel antimicrobial treatments, and chronic wound infection.

PGCTHE: Cardiff Metropolitan University (2012)
PhD Microbiology: University of Reading (2006)
BSc (hons) Microbiology: University of Nottingham (2002)

Fellow of the Institute of Biomedical Sciences (FIBMS)
Fellow of the Higher Education Authority
Chartered Biologist​

My research focusses understanding the interactions between pathogens and their host during the infection process.  The overarching aim of these studies is to understand how pathogens utilise or disrupt host processes and to explore and exploit novel ways of impairing these host-pathogen interactions to facilitate clearance of infection.  These principles enable a targeted approach to infectious disease control in an era where the conservation of traditional antimicrobial treatments is paramount.  This central focus of my research includes biofilm and co-culture models, genomic and molecular analysis of gene expression to prove clinically relevant hypotheses.

Collaborations:  Universities of Warwick, University of Strathclyde, University of Bristol, Khon Kaen University (Thailand), University of Washington (USA), Teeside University, University Hospital W​​ales.

Supervision:  I have supervised one PhD to completion; I currently supervise three PhD students and co-supervise three PhD students.  I supervise MSc, MRes and BSc dissertation students projects as well as summer studentship research projects and ERASMUS placements

1. Srichaiyapol, O., Maddocks, S. E., Thammawithan, S., Daduang, S., Klaynongsruang, S. and Patramanon, R. (2022) TA-AgNPs/alginate hydrogel and its potential application as a promising antibiofilm material against polymicrobial wound biofilms using a unique biofilm flow model. Microorganisms 10: 2279
2. Reeves, N., Phillips, S., Hughers, A., Maddocks, S. E., Bates, M., Torkington, J., Robins, L. and Cornish, J. (2022) Volatile organic compounds in the early diagnosis of non-healing surgical wounds: A systematic review." International Wound Journal doi: 10.1007/s00268-022-06548-3.
3. Nedelea, A-G., Plant, R. L., Robins, L. I and Maddocks, S. E. (2021) Testing the efficacy of topical antimicrobial treatments using a two- and five-species chronic wound biofilm model. Journal of Applied Microbiology doi.10.1111/jam15239
4. Rehman, S. U., Day, J., Afshar, B., Rowlands, R. S. Billam, H., Joseph, A., Guiver, M., Maddocks, S. E., Chalker, V. J and Beeton M. L. (2021) Molecular exploration for Mycoplasma amphoriforme and Ureaplasma spp. from patient samples previously investigated for Mycoplasma pneumoniae infection. Clinical Microbiology and Infection doi.10.1016/j.cmi.2021.06.012
5. Rowlands R.S, Kragh K, Sahu, S, Maddocks S.E, Bolhuis A, Spiller O. B and Beeton M. L. (2021) An essential requirement for flow to enable the development of Ureaplasma parvum biofilms in vitro. Journal of Applied Microbiology. doi:10.1111/jam.15120
6. Harrison, F., Allan, R. N. and Maddocks, S. E. (2020) Polymicrobial Biofilms in Chronic Infectious Disease. Frontiers in Cellular and Infection Microbiology. Editorial. Doi 10.3380/fcimb.2020.628584
7. Duckworth, P. F. Maddocks, S. E., Rahatekar, S. S., Barbour M. E. (2020) Alginate films augmented with chlorhexidine hexametaphosphate particles provide sustained antimicrobial properties for application in wound care. J Mater Sci Mater Med. 31(3):33. doi: 10.1007/s10856-020-06370-0
8. Samuriwo, R and Maddocks S. E. (2019) Antibiotic stewardship: a case for decision-making research. Journal of Wound Care. Editorial. 27: 635
9. Duckworth, P. F., Rowlands, R. S., Barbour, M. E. and Maddocks S. E. (2018) A novel flow system to establish experimental biofilms for modelling chronic wound infection and testing the efficacy of wound dressings. Microbiological Research. 215: 141-147.
10. Alves, P.M., Al-Badi, E., Withycombe, C., Jones, P.M., Purdy, K.J., Maddocks, S.E. (2018). Interaction between Staphylococcus aureus and Pseudomonas aeruginosa is beneficial for colonisation and pathogenicity in a mixed-biofilm. Pathogens and Disease doi: 10.1093/femspd/fty003
11. Pascoe, M. J., Lueangsakulhai, J., Ripley, D., Morris, R. H., and Maddocks, S. E. (2018) Exposure of Escherichia coli to human hepcidin results in differential expression of genes associated with iron homeostasis and oxidative stress. FEMS Microbiology Letters. 365: doi.org/10.1093/femsle/fny089
12. Jayal, A., Johns, B. E., Purdy, K. J. and Maddocks S. E. (2017). Draft genome sequence of Pseudomonas aeruginosa ATCC9027, originally isolated from an outer ear infection. Genome Announc 5:e01397-17
13. Withycombe, C. E., Purdy, K. J. and Maddocks, S. E. (2016) Micromanagement: Curbing chronic wound infection. Molecular Oral Microbiolog

• Member of the Royal Society of Biology
  
• Member of the Microbiology Society
  
• Fellow of the Institute of Biomedical Sciences
  
• Member of the Royal Society of Biology Membership Advisory Committee
  
• Member of the editorial board of “The Biologist”; published by Royal Society of Biology
  
• Member of the Microbiology Society Professional Development Committee
  
• Member of the Microbiology Society Prokaryotic Division
  
• Review Editor the Editorial Board of Frontiers in Cellular and Infection Microbiology
  

Twitter: @SarahMaddocks

Linked In: https://uk.linkedin.com/in/sarah-maddocks-1b740848​