Dr Lowri Mainwaring

​Dr Lowri Mainwaring

bilingual.jpg

Job Title:           Senior Lecturer and Programme Director - Healthcare Science
Room No:          D2.01d
Telephone No: +44 (0) 2920 20 5608
Email Address:  lomainwaring@cardiffmet.ac.uk

 

Teaching

I teach on a number of undergraduate programmes within the department of Biomedical Sciences including Healthcare Science (Life Sciences), Biomedical Science and Biomedical Sciences (Health, Exercise and Nutrition). In addition I teach on the MSc Biomedical Science programme that we deliver within the department.

Modules I deliver include: Professional studies, Principles and practices of Blood Science, Contemporary topics in Healthcare Science, Pathophysiology of disease, Medical Biochemistry, Biology and Laboratory Investigation of Disease as well as specialism modules in blood science. In addition I offer both undergraduate and masters level student projects in my specialist subject area of medical biochemistry.  

I am currently the programme director for the BSc Healthcare Science (Life sciences) programme here at Cardiff Metropolitan University. This programme is the only one of its kind in Wales and incorporates periods of NHS laboratory placements in each year of study.

Modules I am involved with:

Undergraduate

APS4006 Professional Studies – Module leader

APS4010 Personal and professional development A – (Module lead)

APS5012 Principles and practices of Blood Science

APS5018 Blood Science – Specialism A – (Module lead)

APS5022 Professional Practice and Work-Base Training A

APS6008 Contemporary Topics in Biomedical Science

APS6013 Contemporary Topics in Healthcare Science

APS6014 Blood Science – Specialism B

APS6018 Professional Practice and Work-Base Training B

APS6019 Research Project (Healthcare Science)

APS6020 Biology and Laboratory Investigation of Disease

APS6022 Research Project (Biomedical Science)

SBM5001 Pathophysiology of Disease

Postgraduate

MBS7000 Medical Biochemistry – (Module lead)

MBS7001 Advanced Medical Biochemistry – (Module lead)

MBS7010 Dissertation

MBS7021 Analytical and Diagnostic Techniques

Research

During my PhD I investigated the role of the dietary lipid conjugated linoleic acid (CLA) specifically looking at its involvement in the development of the long term complications of type two diabetes mellitus and other inflammatory disorders. I predominantly worked with the cultured cell lines THP-1 (monocytes) and HUVEC (endothelial).

During this project I utilised a number of laboratory methodologies, with the main focus being on the use of Real-Time PCR to ascertain changes in genes relevant to type two diabetes mellitus and its long term complications.

Publications

1.  Caddy, J., Isa, S., Mainwaring, LS., Adam, E., Roberts, AW., Lang, D., Morris, KR., Thomas, AW., Webb, R. (2010) "Rosiglitazone induces the unfolded protein response, but has no significant effect on cell viability, in monocytic and vascular smooth muscle cells" Biochem Biophys Res Comm 400: p. 689-695.

2.  Isa, S.A., Mainwaring, L.S., Webb. R. and Thomas, A.W. (2009): "The Non-Genomic Effects of High Doses of Rosiglitazone on Cell Growth and Apoptosis in Cultured Monocytic Cells" Bayero Journal of Pure and Applied Sciences 2(2): pp.1-8.

3.  Mainwaring, L. S., Bolusani, H., Morris, K., Webb, R. (2008) Dietary supplementation with CLA triggers PPARγ-dependent and PPARγ-independent effects in the leukocytes of patients with metabolic syndrome (CODHy, Barcelona).

4.  Mainwaring, L. S., Bolusani, H., Evans, M., Webb, R., Thomas, A., Morris, K. (2009) The Natural PPARγ Ligand CLA regulates AGER isoform expression in patients with metabolic syndrome (International Congress on Prediabetes and the Metabolic Syndrome, Nice).

External Links

All Wales Biomedical Scientist Trainers Forum
Employers Liaison Panel
All Wales Life Science Integrated Training and Education Group
Practitioner Training Programme Special Interest Group
Fellow of the Higher Education Academy
Member of the Institute of Biomedical Science
Registrant with the Health and Care