Dr Zaheer Yousef




Honorary Reader

BSc (Hons): First Class; University of London
MB BS; University of London
MRCP; Royal College of Physicians (London)
MD; University of London 
FESC; Fellow of the European Society of Cardiology
FRCP; Fellow of the Royal College of Physicians

Consultant cardiologist & Senior Lecturer (honorary) University Hospital of Wales & Cardiff University
Lead Clinician: heart failure & cardiomyopathies, cardiac resynchronisation therapy,
Clinical lead: myocardial inter-disciplinary research group (Cardiff University)
Chair: South Wales Cardiac Network (heart failure committee)

Membership of Professional Bodies

Research Profile
Optimised beta blocker therapy in heart failure: is there space for additional heart rate control? SJ Russell, M Oliver, L Edmunds, J Davies, H Rose, H Llewellyn-Griffiths, V Sim, A Raybould, R Anderson, ZR Yousef. British Journal of Cardiology 2011;18:XX 

Elwyn G, Hardisty A, Peirce S, May C, Evans R, Robinson D, Bolton C, Yousef Z, Conley E, Rana O, Gray A, Preece A.  Detecting deterioration in patients with chronic disease using telemonitoring: navigating the 'trough of disillusionment' Journal of Evaluation in Clinical Practice in press

DE Thomas, ZR Yousef, TD Kinnaird, RA Anderson. The value of using fractional flow reserve measurements in helping to diagnose acute left ventricular failure in the presence of normal left ventricular systolic function. Cardiovascular Revascularization Medicine 2011;12:181-3.

Beadle RM, Williams LK, Abozguia K, Patel K, Leyva-Leon F, Yousef Z, Wagenmakers A, Frenneaux MP. Metabolic manipulation in chronic heart failure: study protocol for a randomised controlled trial. Trials 2011;12:140.

Anderson RA, Thomas DE, Yousef ZR. Novel pharmacological interventions to maintain sinus rhythm after DC cardioversion. ISRN Cardiology in press

Thomas DE, Exton SA, Yousef ZR.  Heart rate deceleration after exercise predicts patients most likely to respond to cardiac resynchronisation therapy. Heart 2010;96:1385.

Thomas DE, Wheeler R, Yousef ZR, Masani ND. The role of echocardiography in guiding management in dilated cardiomyopathy. European Journal of Echocardiography 2009;10:15-21.

V M-F Sim, M Nam, S Riley, Z Yousef, J Hurley, W-Y Cheung, S O'Mahony. Anaemia in older people with chronic heart failure: the potential cost. Technology and Health Care 2009;17:1-10

ZR Yousef, K Khadjooi, PWX Foley, S Chalil, H Sandemann, NUH M F Leyva. Left ventricular non-compaction: clinical features and cardiovascular magnetic resonance imaging. BMC Cardiovascular Disorders 2009, 9:37

T-P Phan, G Shivu, A Choudhury, K Abozguia, C Davies, U Naidoo, I Ahmed, Z Yousef, J Horowitz, M Frenneaux. Multi-centre experience on the use of perhexiline in chronic heart failure and refractory angina: old drug, new hope. European Journal of Heart Failure. 2009;11:881.

DE Thomas, ZR Yousef, AG Fraser. Methodology, feasibility and utility of echo-guided CRT optimisation. Back to basics? European Journal of Heart Failure 2009;11:779-88

JS Taylor, R Purnell, ZR Yousef. Acquired left ventricular outflow tract obstruction and cardiogenic shock treated with beta-blockers. American Journal of Emergency Medicine 2009;27:373.e1-373.e3

A Zagler, TB Heimowitz, E Escolar, SJ Hussein, ZR Yousef, P Gabriel-Steg, V Dzavik, JS Hochman, PA Vignola, GA Lamas. A Late Intervention on an Occluded Infarct-Related Artery: A Meta-analysis of The Randomized Controlled Trials.  Clinical medicine: cardiology 2007;1:25-32.

S Chalil, PW Foley, SA Muyhaldeen, KC Patel, ZR Yousef, RE Smith, MP Frenneaux, F Leyva. Late gadolinium enhancement-cardiovascular magnetic resonance as a predictor of response to cardiac resynchronization therapy in patients with ischaemic cardiomyopathy.  Europace 2007;9:1031-1037.

ZR Yousef, S Chalil, SA Muyhaldeen, REA Smith, P Jordan, CR Gibbs, F Leyva. Pacing-induced increase in QTc dispersion predicts sudden cardiac death following cardiac resynchronization therapy.  Journal of the American College of Cardiology 2006;47:2486-2492.

ZR Yousef, V Paul, F Leyva. Cardiac resynchronisation via the femoral vein: a novel approach in anatomically challenging cases.  Europace 2006;8:144-46.

ZR Yousef, SR Redwood, MS Marber. Has the time come to open all occluded infarct-related arteries? Heart 2005;91:561-2.

NG Bellenger, Z Yousef, , K Rajappan MS Marber DJ Pennell. Infarct zone viability influences ventricular remodelling following late recanalization of an occluded infarct related artery.  Heart 2005;91:478-483.

ZR Yousef, F Leyva, C Gibbs. Angiotensin receptor blockers and myocardial infarction: cautions voiced are biologically credible.  British Medical Journal 2005;330(7502):1270.

ZR Yousef, Tandy SC, Tudor V, Jishi F, Trent RJ, Watson DK, Cowell RPW. Warfarin for non-rheumatic atrial fibrillation: 5-year experience in a District General Hospital.  Heart 2004;90:1259-1262.

F Jishi, PR Hudson, CP Williams, RP Jones, GK Davies, ZR Yousef, RJ Trent, RPW Cowell. Troponin I, laboratory issues and clinical outcomes in a DGH: Cross-over study with 'traditional'  markers of myocardial infarction in a total of 1990 patients.  Journal of Clinical Pathology 2004;57:1027-32.

ZR Yousef, SR Redwood, CA Bucknall, AN Sulke, MS Marber. Detrimental effects of late artery opening. Journal of the American College of Cardiology 2003;41:1067-9.

ZR Yousef, SR Redwood, CA Bucknall, AN Sulke, MS Marber. Late intervention after anterior myocardial infarction: effects on left ventricular size, function, quality of life and exercise tolerance. Results of the open artery trial (TOAT study).  Journal of the American College of Cardiology 2002;40:869-76.

R Edwards R, Z Yousef, R Rakhit, M Wright, E Rosenthal, S Redwood, M Marber. A model of closed chest regional myocardial infarction in the rabbit: a clinically relevant in vivo assay system of post-infarction remodelling.  Basic Research in Cardiology 2002; 97:374-83.

ZR Yousef, MS Marber. The open artery hypothesis: mechanisms of benefit.  Progress in Cardiovascular Disease 2000;46:419-439.

ZR Yousef, SR Redwood, MS Marber. Post-infarction left ventricular remodelling: where are the theories and trials leading us?  Heart 2000;83:76-80.

ZR Yousef, SR Redwood, MS Marber. Post-infarction left ventricular remodelling: a pathophysiological and therapeutic review.  Cardiovascular Drugs & Therapy 2000;14:243-252.

ZR Yousef, D Brennand-Roper, MS Marber. Sildenafil (Viagra) and myocardial infarction.  British Journal of Cardiology 1999;6:335-339.

RG Dent, DR Boniface, J Fyffe, Z Yousef. The effects of time delay and temperature on capillary blood gas measurements.  Respiratory Medicine 1999;93(11):794-797.

Publications (others)
Deputy Editor: Cardiology News (2005 to date)

Textbook of Cardiovascular Genetics: chapter on left ventricular non-compaction

ZR Yousef, MS Marber. The National Service Framework for Coronary Artery Disease: implications for primary and secondary care in general practice.  GP Update 2000;Nov:536-541.​